Radiochemical purity and particles number determinations of modified 99mTc-macroaggregated albumin
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چکیده
منابع مشابه
Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals.
The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the temperatures can be higher than those reported in the commercial illustrative leaflets of the kits. This is due, in particular, to the small size of the wo...
متن کاملPrognostic utility of 90Y radioembolization dosimetry based on fusion 99mTc-macroaggregated albumin-99mTc-sulfur colloid SPECT.
UNLABELLED Planning hepatic (90)Y radioembolization activity requires balancing toxicity with efficacy. We developed a dual-tracer SPECT fusion imaging protocol that merges data on radioactivity distribution with physiologic liver mapping. METHODS Twenty-five patients with colorectal carcinoma and bilobar liver metastases received whole-liver radioembolization with resin microspheres prescrib...
متن کاملPreparation, radiochemical purity control and stability of 99mTc-mertiatide (Mag-3).
BACKGROUND Scintigraphic image analysis of 99mTc-mertiatide (Mag-3, mercaptoacetyltriglycine) clearance provides the determination of the blood flow, the tubular transit time and the excretion as well from both kidneys. Radiopharmaceutical routine recommends a radiochemical purity control before administration of the product to a patient. The main objective of this study is to develop a Mag-3 l...
متن کاملParticle-size and radiochemical purity evaluations of filtered 99mTc-sulfur colloid prepared with different heating times.
UNLABELLED Sentinel node lymphoscintigraphy using colloidal particles has become common practice at many institutions. The ideal particle size for colloids such as filtered (99m)Tc-sulfur colloid ((99m)Tc-FSC) in sentinel node studies is 15-100 nm. It is reported that the use of a reduced heating time during the reconstitution process results in an increased number of smaller particles (<30 nm)...
متن کاملDetermination of the radiochemical purity of 99mTc- tetrofosmin: Comparison between five methods
METHODS: Nineteen vials of tetrofosmin were radiolabelled with Tc and the percentages of the RCP were determined. Five different methods were compared with the standard RCP testing method (ITLC-SG, 2x20 cm): Whatman 3MM (1x10 cm) with acetone and dichloromethane (method 1); Whatman 3MM (1x10 cm) with ethyl acetate (method 2); aluminum oxide-coated plastic thin-layer chromatography (TLC) plate (...
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ژورنال
عنوان ژورنال: Journal of the Serbian Chemical Society
سال: 2002
ISSN: 0352-5139,1820-7421
DOI: 10.2298/jsc0209573d